Samaritan Infectious Disease - Antibiotic Table

Antibiotic	Indications	Adverse Reactions	Comments
Ertapenem	Intra-abdominal infections Skin and soft tissue infection	Diarrhea Rash/allergy	Once daily administration - useful for outpatient infusion; no anti-pseudomonal activity; only parenteral
Erythromycin	Pertussis Legionellosis Grp A strep pharnygitis (alternative to pen)	Diarrhea	Other macrolides better tolerated; possible drug interactions
Gentamicin	UTI Intra-abdominal infections Synergistic therapy of endocarditis Plague/tularemia	Nephrotoxicity Otovestibular toxicity	Once daily administration is less toxic; avoid in older diabetics and the elderly
Imipenem	Broad spectrum coverage of serious infection Healthcare associated pneumonia Sepsis Neutropenic fever	Seizure potential	Intrinsic resistance in stenotrophomonas; poor stability for outpatient infusion
Levofloxacin	Community acquired pneumonia Drug resistant Streptococcus pneumoniae	Hypo/hyperglycemia QTc prolongation Tendinopathy Photosensitivity	Ciprofloxacin has better anti-pseudomonal activity and is preferred for Rx of UTI and intra-abdominal infections; association with C. diff.
Linezolid	MRSA VRE	Thrombocytopenia Serotonin syndrome Neurotoxicity	Excellent bioavailability; expensive; failure of therapy can occur in bloodstream infection
Meropenem	Broad spectrum coverage of serious infection Sepsis	Rash/allergy	Similar spectrum to that of imipenem; less seizure risk
Metronidazole	Anaerobic infections Clostridium difficile Giardia Amebiasis Trichomoniasis Bacterial vaginosis	Foul taste Neurotoxicity (prolonged use)	Excellent bioavailability; disulfiram-like reaction with alcohol
Moxifloxacin	Community acquired pneumonia Non-tuberculous mycobacterial infections	Hypo/hyperglycemia QTc prolongation Tendinopathy Photosensitivity	Hepatically excreted - not indicated for UTI; association with C. diff.

First

Last

Drug Information provided above is not comprehensive. For complete information about these antibiotics consult a pharmacist or a comprehensive drug reference.