Samaritan Infectious Disease - Antibiotic Table

Antibiotic	Indications	Adverse Reactions	Comments
Ceftriaxone	CAP Pyelonephritis Bacterial meningitis Gonorrhea Neuroborreliosis	Rash/allergy Biliary/gallbladder sludge	Broad spectrum; once daily administration - useful for outpatient infusion; association with C. diff infection
Cefuroxime	Sinusitis Cellulitis	Rash/allergy	2nd generation cephalosporin, p.o. and IV forms
Ciprofloxacin	UTI/pyelonephritis Intra-abdominal infection	Hypo/hyperglycemia QTc prolongation Tendinopathy Photosensitivity	Not as active against respiratory pathogens as respiratory quinolones; assocation with C. diff infection; drug interactions
Clarithromycin	Non-tuberculous mycobacteria H. pylori	Diarrhea	Azithromycin is often better tolerated; drug interactions
Clindamycin	Anaerobic infection Aspiration pneumonia Odontogenic infection Skin and soft tissue infection	Diarrhea Rash/allergy Dysguesia	Associated with C. diff infection; Beta strep not universally susceptible; effective against some strains of MRSA; B. fragilis resistance
Dalbavancin	Skin and soft tissue infections due to susceptible GPC	Nausea, vomiting Rash, "Red-Man"	Effective against GPC including MRSA and VISA; not active against VRE
Daptomycin	MRSA VRE	Rhabdomyolysis Eosinophilic pneumonitis	Ineffective in treatment of pneumonia; only available parenterally
Doripenem	Intra-abdominal infection Complicated UTI Nosocomial pneumonia	Nausea, vomiting Rash/allergy	Similar spectrum of activity to imipenem, meropenem
Doxycycline	Many zoonotic illnesses (lyme, ehrlichia, rickettsia) Minor MRSA skin infections Malaria prophylaxis Chlamydia	Photosensitivity "Pill" esophagitis	Versatile, multiple uses; excellent bioavailability; no need to adjust dose for renal insufficiency

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Drug Information provided above is not comprehensive. For complete information about these antibiotics consult a pharmacist or a comprehensive drug reference.