Antibiotics Printable View

Antibiotic
Indications

Adverse Reactions

Comments
Telithromycin
  • Mild to moderately severe CAP (second line)
  • Nausea, vomiting
  • LFT elevation
Rare fulminant hepatitis; FDA withdrew indications for sinusitis, AECB accordingly
Ticarcillin/Clav
  • Broad spectrum agent for serious infection
  • Pseudomonas
  • Stenotrophomonas
  • Rash/allergy
  • Hypokalemia
Relatively inactive against enterococci; currently unavailable in U.S.
Tigecycline
  • Resistant GNR and GPC
  • MRSA
  • VRE
  • Nausea
Low serum levels - not advised for bloodstream infections
TMP/SMX
  • Cystitis
  • Minor MRSA infections
  • Pneumocystis pneumonia
  • Sinusitis
  • Rash
  • Hypersensitivity
  • Nephrotoxcity
Excellent bioavailability
Tobramycin
  • Gram neg infections
  • Intra-abdominal infections
  • UTI
  • Nephrotoxicity
  • Otovestibular toxicity
More active than gentamicin against pseudomonas
Unasyn/Augmentin
  • Bite wound infections
  • CAP
  • Diabetic foot infections
  • Biliary infections
  • Diarrhea
  • Rash/allergy
Excellent anaerobic activity; Unasyn (IV) and Augmentin (p.o.) have similar antimicrobial activity
Vancomycin
  • Serious MRSA infections
  • C. diff (p.o.)
  • Alternative antibiotic for pen allergy
  • Prosthetic device infections
  • Red man's syndrome
  • Nephrotoxicity
  • Otovestibular toxicity
  • Cytopenias
Less effective than beta-lactam antibiotics for methicillin sensitive Staph aureus

 

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Drug Information provided above is not comprehensive. For complete information about these antibiotics consult a pharmacist or a comprehensive drug reference.