Proteus mirabilis

Antibiotic
% Susceptible
2010
% Susceptible
2012
% Susceptible
2014
% Susceptible
2016
% Susceptible
2018
Ampicillin
60
70 75 80 81
Azithromycin
-*
-*
-*
-* -*
Aztreonam
98
99
98
98 100
Cefazolin
83
89
91
91 89
Cefepime
98
99
99
100 100
Ceftazidime
97
98
99
99 99
Ceftriaxone
97
99
99
98 98
Cefuroxime
95
97
98
97 98
Ciprofloxacin
62
63
72
74 77
Clarithromycin
-*
-*
-*
-* -*
Clindamycin
-*
-*
-*
-* -*
Doxycycline
2
0
0
0 -
Erythromycin
-*
-*
-*
-* -*
Gentamicin
95
91
92
86 89
Imipenem
98
100
99
+ +
Levofloxacin 65 68 75 76 79
Meropenem + 100 100 100 100
Moxifloxacin + + + + +
Nitrofurantoin 0 0 0 0 0
Oxacillin/Naf - - - - -
Penicillin - - - - -
Piperacillin 78 85 86 + +
Piperacillin/tazo 100 100 100 100 100
Ticarcillin/Clav + + + + +
Tobramycin 95 93 94 91 90
TMP/SMX 60 63 74 76 77
Unasyn/Aug 90 91 91 91 91
Vancomycin -* -* -* -* -*
       
# Tested 452 523 426 471 542

Comments:  

 

Numeric data represent local susceptibility data.
(+) = usually effective or >60% susceptible; (+/-) = clinical trials lacking or 30-60% susceptible; (-) = not effective clinically or <30% susceptible - Adapted with permission from The Sanford Guide to Antimicrobial Therapy
(*) Local (non-Sanford Guide) opinion
(S) = synergistic with penicillin/ampicillin;
(&) nitrofurantoin only useful for lower tract urinary tract infections