Infectious Diseases Case of the Month
       
Peri-oral sore in a 2 y.o.

A 2 y.o. hispanic male was admitted to Munson Medical Center for apparent failure of outpatient therapy for an orolabial/peri-oral sore.

Several days prior to admission he had developed a sore at the left corner of his mouth (oral commissure) for which he had been brought for medical attention two days prior to admission. According to his mother he also may have had some sore throat and slight cough at the onset of his illness. At the time of his outpatient evaluation he was described as having a small scab at the oral commissure with a 1 cm area of adjacent induration without vesiculation. He was placed on oral TMP/SMX. When there was apparent progression despite the antibiotic, he was admitted to the hospital two days later. At the time of admission there was obvious discomfort associated with the lesion, but the child otherwise appeared well, was able to eat, and was afebrile. Admission labs included WBC 14.8, Hgb 12.3, Plts 382.

He was born in Traverse City, MI of Mexican-born parents whose primary language remained Spanish. He had not traveled to Mexico since birth, had been in good health, and had received normal childhood immunizations. Several months prior to admission he had had a 3 x 3 cm carbuncle on this buttock that resolved with incision and drainage and oral cephalexin.

The patient had specimens obtained for culture and was placed on IV antibiotics.

 

What was the most likely cause of this patient's orolabial/peri-oral abnormality?
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What was the likely cause of the patient's febrile illness?

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